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Virtual Microscopy / NanoZoomer - Technology
Principle | Questions and Answers

HAMAMATSU's core business and know-how is developing and manufacturing opto-electronic technology and products since 1948. With more than 14% of the turnover reinvested in research and development, HAMAMATSU is one of the most innovative companies, providing new solutions for the industrial, medical and research fields.

HAMAMATSU SYSTEM DIVISION integrates components (sensors, electronics, illumination devices, etc.) of other HAMAMATSU DIVISIONS into powerful integrated systems adapted to customers' needs.

This multidisciplinary approach allows us to bring reliable systems to the market that are based on the latest innovative opto-electronic technology.

The NanoZoomer is a product of years of experience and collaboration with research and medical laboratories. And, our previous experience in the design of high throughput screening systems was valuable in providing the NanoZoomer with the required mechanical reliability that is needed.

HAMAMATSU originally developed time-delay-and-integration (TDI) technology for solving certain demanding tasks in space science. Surprisingly, some of the technological requirements for a high-performance slide scanner turned out to be identical to that of these space applications, which gave us a head start in bringing this hi-tech solution to the world of virtual microscopy.

As a result, the HAMAMATSU TDI scanning method allows the achievement of high-speed scanning without sacrificing image quality. For example, it is now possible to scan an entire mouse embryo (approximately 10 mm x 10 mm area) at 20x magnification in less than a minute. In addition, the high light sensitivity of TDI is sufficient even for fluorescence imaging, which is why a NanoZoomer scanner can be upgraded to fluorescence capability without exchanging the light sensor.

 
 
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